Wednesday, November 27, 2019

Research on Pregnancy for the Male Seahorse

Research on Pregnancy for the Male Seahorse Free Online Research Papers The reproductive questions surrounding seahorses and pipefish (syngnathids), specifically about why males are the gender which undergoes pregnancy, are pondered and researched in the article I chose. This article describes the similarities and differences between mammal and seahorse viviparity, â€Å"extended embryonic development inside a parent,† (Stolting K, Wilson A, 2007) especially several key parallels, such as types of hormones needed, which were discovered through this experiment, and mentions several ideas for future research on these creatures. Seahorses are one of the few kinds of sea animals that can be readily cultured in a lab; they also have a short generation time (3-12 months), lots of offspring (50-2000 offspring per brood), and a small genome size, which make them ideal as a model for future morphological, behavioral, and reproductive experiment research. (Foster, Vincent, 2004). First, descriptions of the seahorse’s reproductive nature are described and compared to that of mammals and marsupials. Then the two types of seahorses are compared, and we examine the experiment. The experiment measured the hormones of male seahorses during pregnancy, both as normal and others with missing hormones, to compare the hormones used/needed by seahorses for reproduction and pregnancy. The article then claims that because hormones needed for successful seahorse pregnancies and mammal pregnancies are the same or very similar that there should be further research in this area to explore further details into why, now that we know more about how seahorses function. Research Papers on Research on Pregnancy for the Male SeahorseInfluences of Socio-Economic Status of Married MalesPersonal Experience with Teen PregnancyMoral and Ethical Issues in Hiring New EmployeesResearch Process Part OneEffects of Television Violence on ChildrenGenetic EngineeringThe Relationship Between Delinquency and Drug UseAnalysis of Ebay Expanding into AsiaMind TravelBionic Assembly System: A New Concept of Self

Saturday, November 23, 2019

Daniel OConnell - Biography of Irish Statesman

Daniel OConnell - Biography of Irish Statesman Daniel OConnell was an Irish patriot who came to exert enormous influence on the relationship between Ireland and its British rulers during the first half of the 19th century. OConnell, a gifted orator, and charismatic figure rallied the Irish people and helped secure some degree of civil rights for the long-oppressed Catholic population. Seeking reform and progress through legal means, OConnell was not really involved in the periodic Irish rebellions of the 19th century. Yet his arguments provided the inspiration for generations of Irish patriots. OConnells signature political achievement was the securing of Catholic Emancipation. His later Repeal Movement, which sought to repeal the Act of Union between Britain and Ireland, was ultimately unsuccessful. But his management of the campaign, which included Monster Meetings which drew hundreds of thousands of people, inspired Irish patriots for generations. It is impossible to overstate the importance of OConnell to Irish life in the 19th century. After his death, he became a venerated hero both in Ireland and among the Irish who had emigrated to America. In many Irish-American households of the 19th century, a lithograph of Daniel OConnell would hang in a prominent location. Childhood in Kerry O’Connell was born on August 6, 1775, in County Kerry, in the west of Ireland. His family was somewhat unusual in that while Catholic, they were considered members of the gentry, and they owned land. The family practiced an ancient tradition of â€Å"fosterage,† in which a child of wealthy parents would be raised in the household of a peasant family. This was said to make the child deal with hardships, and other advantages would be that the child would learn the Irish language as well as local traditions and folklore practices. In his later youth, an uncle nicknamed â€Å"Hunting Cap† O’Connell doted on young Daniel, and often took him hunting in the rough hills of Kerry. The hunters used hounds, but as the landscape was too rough for horses, the men and boys would have to run after the hounds. The sport was rough and could be dangerous, but young O’Connell loved it. Studies in Ireland and France Following classes taught by a local priest in Kerry, O’Connell was sent to a Catholic school in the city of Cork for two years. As a Catholic, he couldn’t enter the universities in England or Ireland at the time, so his family sent him and his younger brother Maurice to France for further studies. While in France, the French Revolution broke out. In 1793 O’Connell and his brother were forced to flee the violence. They made their way to London safely, but with little more than the clothes on their backs. The passing of Catholic Relief Acts in Ireland made it possible for O’Connell to study for the bar, and in the mid-1790s he studied at schools in London and Dublin. In 1798 O’Connell was admitted to the Irish bar. Radical Attitudes While a student, O’Connell read widely and absorbed current ideas of the Enlightenment, including such authors as Voltaire, Rousseau, and Thomas Paine. He later became friendly with the English philosopher Jeremy Bentham, an eccentric character known for advocating a philosophy of â€Å"utilitarianism.† While O’Connell remained a Catholic for the rest of his life, he also always thought of himself as a radical and a reformer. Revolution of 1798 A revolutionary fervor was sweeping Ireland in the late 1790s, and Irish intellectuals such as Wolfe Tone were dealing with the French in hopes that French involvement could lead to Ireland’s liberation from England. O’Connell, however, having escaped from France, was not inclined to align himself with groups seeking French aid. When the Irish countryside erupted in rebellions of the United Irishmen in the spring and summer of 1798, O’Connell was not directly involved. His allegiance was actually to the side of law and order, so in that sense, he sided with British rule. However, he later said that he wasn’t approving of the British rule of Ireland, but he felt that open revolt would be disastrous. The 1798 uprising was particularly bloody, and the butchery in Ireland hardened his opposition to violent revolution. Legal Career of Daniel OConnell Marrying a distant cousin in July 1802, O’Connell soon had a young family to support. And though his law practice was successful and constantly growing, he was also always in debt. As O’Connell became one of the most successful lawyers in Ireland, he was known for winning cases with his sharp wit and extensive knowledge of the law. In the 1820s O’Connell was deeply involved with the Catholic Association, which promoted the political interests of the Catholics in Ireland. The organization was funded by very small donations which any poor farmer could afford. Local priests often urged those in the peasant class to contribute and become involved, and the Catholic Association became a widespread political organization. Daniel OConnell Runs for Parliament In 1828, OConnell ran for a seat in the British Parliament as the member from County Clare, Ireland. This was controversial as he would be barred from taking his seat if he won, as he was Catholic and Members of Parliament were required to take a Protestant oath. OConnell, with the support of poor tenant farmers who often walked miles to vote for him, won the election. As a Catholic Emancipation bill had recently passed, due in large measure to agitation from the Catholic Association, OConnell was eventually able to take his seat. As might be expected, OConnell was a reformer in Parliament, and some called him by the nickname, The Agitator. His great goal was to repeal the Act of Union, the 1801 law which had dissolved the Irish Parliament and united Ireland with Great Britain. Much to his despair, he was never able to see Repeal become a reality. Monster Meetings In 1843, OConnell mounted a great campaign for Repeal of the Act of Union and held enormous gatherings, called Monster Meetings, across Ireland. Some of the rallies drew crowds of up to 100,000. The British authorities, of course, were greatly alarmed. In October 1843 OConnell planned a huge meeting in Dublin, which British troops were ordered to suppress. With his aversion to violence, OConnell canceled the meeting. Not only did he lose prestige with some followers, but the British arrested and jailed him for conspiracy against the government. Return to Parliament OConnell returned to his seat in Parliament just as the Great Famine ravaged Ireland. He gave a speech in the House of Commons urging aid for Ireland and was mocked by the British. In poor health, OConnell traveled to Europe in hopes of recuperating, and while en route to Rome he died in Genoa, Italy on May 15, 1847. He remained a great hero to the Irish people. A grand statue of OConnell was placed on the main street of Dublin, which was later renamed OConnell Street in his honor.

Thursday, November 21, 2019

Marketing Assignment Example | Topics and Well Written Essays - 500 words - 15

Marketing - Assignment Example Online or web based surveys requires little money to complete the process. The person contacting the survey only needs to create a website or have the survey hosted in another website. The surveyor incurs the cost of internet and webhosting or creation of a website. The respondents have to pay internet bill in order to complete the survey. On the other hand, traditional surveys are more expensive, since they need more materials and work. In the traditional survey, an individual need more people to contact the survey. Transport cost is also needed in order to reach the respondents. The online surveys are less expensive than the traditional surveys. Better reach is another benefit of using the web based survey instead of tradition surveys. The web based or online survey enables the surveyor to reach a large number of people. The use of web based survey enables the surveyor to reach more people without contacting additional interview or scheduling complicated field work. The survey is carried online and anybody with access to internet can participate in the survey. On the other hand, the traditional survey does not reach more people. The surveyor needs to carry out more field work in order to reach more people. It is tiresome to meet more people so traditional survey researcher opts for small number of people. The web based survey carried on online platforms enables an individual to reach more people than the traditional survey research. Finally, web based survey enabled the surveyor to have better targeting. Better targeting benefit is enjoyed by the person carrying out the web based or online survey. Over the internet is simple and easy to target people depending on the interests and behavior. In traditional method an individual can only target people in respect to demographics. The use of web based or online survey enables targeting of respondent, while the traditional method does not allow better targeting. The idea of redesigning

Tuesday, November 19, 2019

The most effective channel structure Essay Example | Topics and Well Written Essays - 3000 words

The most effective channel structure - Essay Example Specification of distribution tasks in order to achieve the set objectives was done using the five task groups namely physical distribution, after sale service, channel support, selling and risk assumption. The next stage involved selecting alternative channel structures using the channel levels, intensity and intermediary levels after which evaluation of the alternatives was done using the weighted factor score approach. This helped to determine the effective channel strategy which was to provide accommodation services so as to reduce costs for tourists hence attract them. This is to differentiate Webjet from the competitors and gain sustainable competitive advantage. An implementation plan was then designed to achieve the results needed. Table of Contents Executive summary 1 Table of Contents 2 List of Tables and Figures 4 1. Introduction 5 1.1 Authorization 5 1.2 Limitation 5 1.3 Scope of Report 5 2. Case Background 6 2.1 Company Background 7 2.2 Channel Design Decision Paradigm 7 3. Major Case Issues 9 4. Situation Analysis 9 4.1 Internal AND EXTERNAL Analysis 9 4.2 INTERNAL ANALYSIS 10 4.3 External Analysis 11 4.4 Setting and Coordinating Distribution Objectives 11 4.5 Distribution Tasks 12 4.5.1 Selling 12 4.5.2 Channel Support 13 4.5.3 Physical Distribution 13 4.5.4 Product modification and after-sales services 14 4.5.5 Risk Assumptions 14 5. Identifying Alternative Channel Structures 14 5.1 Number of Channel Levels 15 5.2 Intensity at Each Level 16 5.3 Types of Intermediaries 16 5.4 Alternative Channel Structure Strategy 16 6. Evaluation of Alternative Channel Structure 17 6.1 Company Variables 17 6.2 Market Variables 18 6.3 Product Variables 19 6.4 Intermediaries Variables 20 6.5 Weighted Factor Score Approach 20 7. Recommended Strategy 21 8. Implementation plan 21 9. Conclusion 22 10. List of References 24 List of Tables and Figures Figure A- Channel Design Paradigm Adapted from (birch, 2006) 9 Figure B - Channel levels in travel agency Adapted FROM ( Holma, 2010) 15 1. Introduction 1.1 Authorization This report has been authorized by Mr. David Clarke to outline the most effective channel structure for Webjet Limited. In the production of the report, the seven steps of the channel decision paradigm will be utilized. 1.2 Limitation Various limitations were noted while conducting research and producing the report. One of the major limitations was not having a clear timeline for completion of the report. This meant the report could be delayed due to lack of urgency and timeline leading to outdated information which has been overtaken by events and also delays in implementation which could lead to severity of the problem. Another limitation was lack of useful and relevant information from the literature and inability to obtain timely communication from Webjet. 1.3 Scope of Report This report examined a number of ways on how to create or modify the channel design of Webjet Limited. This involved looking into the existing channels and determining if they are suitable for the organization and what could be done to improve on them. This was to assist Webjet to recognize the need to make a decision on the channel design. This involved undergoing the seven channel design stages to come up with the right channel for Webjet. Firstly, a brief background was given for the company selected (Webjet) containing company profile, locations, products and company history together with the channel design

Sunday, November 17, 2019

Business Financing and the Capital Structure Essay Example for Free

Business Financing and the Capital Structure Essay The financial marketplace is the area where companies engaged in financial trading are able to get capital to run. The financial market can also be referred to as capital markets. Stock markets are the place where companies come to trade among themselves; they represent individual investors or corporate investors. Trade in stocks has been deemed among the most lucrative areas a person can trade in; the returns are good. Stocks can simply be defined as shares bought for trading purposes and profits gained are ploughed back into the U. S. economy. (Saccomani and Chambers, 2008) Trade in U.S. financial markets offer various benefits; an organization can get loans to fund their activities through floating of bonds. When organizations are able to run efficiently then everybody gets to benefit, the government benefits through increased tax collection and more people get employed. The stock market offer individuals an avenue to put their money in lucrative stock instruments where the funds are managed by financial experts. Individuals do not have to worry about their limited financial expertise because at the stock markets well informed brokers or their employees will help them. Individuals are offered a variety of trading avenues which involves minimal labor and less capital intensive. (Saccomani and Chambers, 2008) The Federal Reserve is a name that is used to define the Central Bank in America. The bank was a creation of U.S. Congress for purpose of offering a safer and easier trading environment in America. The Fed is tasked with the management of the American monetary policy. They also regulate banks as well as monitoring risks at the stock markets. The Fed is comprised of seven members; who constitute the board of governors. Members of the board also constitute the F.O.M.C. (Federal Open Markets Committee); this committee decides on what interest rates to be charged by banks as well as purchase of treasuries. The Fed`s primary role is that of regulation. (Ltaifa et al, 2009) The Fed chairman`s role is that of a supervisor; he is tasked with the role of bringing the board to consensus of various monetary issues. The chairman is a presidential appointee hence he reports to the president from time to time on the country`s financial matters. The chairman also has the responsibility of steering the committee on interest rates. (Ltaifa et al, 2009) Departments or components of the Fed Reserve need to play their respective roles effectively so as to take the country in to financial success. The chairman should always maintain a steady control of all fiscal policies. The board should not enact self-centered policies that may endanger the banking sector or stock markets. The board and the chairman have to make prudent assessments of U.S. financial performance before taking any steps meant at changing any monetary policy. Interest rates affect the economy; particularly the spending power of individuals. The rates charged on bank loans lays a heavy burden on citizens; the net effect is loans become expensive hence doing business becomes harder. Higher interest rates on returns at the stock markets offer a reversed effect to the citizen; this brings about more disposable income because the return on investment is higher. (Batten and Szilagvi, 2011) The world suffers when markets get affected by whatever elements; this happens because the various economies around the world are interconnected hence any financial downfall of one will weaken the other. The Euro zone crisis is one such example where a problem begins in one country but after sometime affects a number of countries within same geographical location; countries that trade together. In the U.S. such a crisis occurred between 2007-2010, individuals found themselves not being able to finance their loans and other credit obligations. Care and keenness is needed when one wishes to traverse this terrain. References Saccomanni, F., Chambers, A. (2008).  Managing international financial instability: National tamers versus global tigers. Cheltenham: Edward Elgar. Ltaifa, Navil Ben, Kaendera, Stella, Dixit, S. V. S. (2009).  Impact of the Global Financial Crisis on Exchange Rates and Policies in Sub-saharan Africa. Intl Monetary Fund. Batten, J., Szilagyi, P. G. (2011).  The impact of the global financial crisis on emerging financial markets. Bingley, U.K: Emerald. Source document

Thursday, November 14, 2019

Macbeth - The Breaking Ball Of Clay :: essays research papers

A conscience and will power are all things we develop over a period of time. You are born pure, like an unshaped ball of clay that is just waiting for a sculpture to shape you. Everything you come into contact with, everyone that helps you grow up and everyone one that you meet seem to take a turn on how you are going to turn out in life. You, a ball of clay is shaped and the person you are today is formed. Although many things change through life, some traights you never thought you had may become apparent or you might acquire new ones. Such is the case with William Shakespeare's Macbeth. The lead character of this play is faced with many decisions and tempted by greed for the throne of Scotland. Many factors affect Macbeth and he slowly rips, committing himself to evil. Banquo and Macbeth meet three witches after defending Scotland against a rebellion. These witches represent evil and they are messengers of the devil. They are one of the factors that affect Macbeth and cause him to enter into a life of evil. They had fought nobly and were very excited. They could not believe their eyes and ask if they had "eaten from the insane root" and were having hallucinations. The witches prophesize that Macbeth, Thane of Fife will soon earn the title, Thane of Cawdor and after that become king of Scotland. Macbeth is "wrapt" in thought about this. At first he wonders if this oracle has any merit. But the true thought of it makes him wonder and starts his early thoughts of conspiracy. He expresses these thoughts to his wife, Lady Macbeth, in a letter. Macbeth rides in a hurry to get home on his horse to talk to Lady Macbeth about her thoughts on the matter. She is totally convinced that Macbeth should kill the king and take his thrown. However Malcolm, the King's son, has already been crowned Prince of Cumberland. Macbeth sees this and drops most thoughts of conspiracy. Lady Macbeth sees this and convinces herself to convince him to commit this crime. She uses a bombardment of arguments to do this against Macbeth. She questions his man hood, and talks about what she would do if she were in his position. Ruthlessly describing scenes of a hardened heart, Lady Macbeth becomes the major factor on Macbeth's decision.

Tuesday, November 12, 2019

Charles Dickens Essay

Comparing the ways in which tension and suspense is created in the opening sequences of David Lean’s 1946 & Julian Jarrold’s 1999 interpretation of â€Å"Great Expectations† by Charles Dickens  In David Lean’s 1946 interpretation of â€Å"Great Expectation† Pip is portrayed as a small, smart, clean young boy, as he will be considered more innocent and vulnerable to the audience. Pip’s fair hair colour against the darkening background makes the audience think that he is an angelic like figure. Lean shows the vast landscape with tall-silhouetted gibbets to indicate just how small and vulnerable Pip is running across the marshland. When Pip goes to visit and weed the grave of his parents, Lean shows this particularly to gain the audience’s sympathy. The audience hears everything that Pip hears and this helps us to understand his apprehension. The scream is shocking and makes us see his fear to his meeting with the convict. When he is being threatened, Pip’s overwhelming politeness and naivety, despite the life-threatening situation he is in, makes the audience feel a great deal of sympathy for him. However, in Julian Jarrold’s 1999 interpretation of â€Å"Great Expectations† Pip is portrayed as a scruffy and an unclean young boy. This image gains the audience’s sympathy as we can tell that he is mistreated at home. Jarrold’s Pip has dark hair; and although he is not seen as an angelic and innocent figure. Jarrold engages the sympathy of the audience by presenting him as a hunted animal. When Pip encounters the convict, he is undoubtedly terrified and traumatised. He cannot even look at the convict, and is so paralysed with fear he can’t even speak. When we first meet the convict we can see immediately how intimidating he can be. David Lean shows a close-up of his face simultaneously to him jumping onto the scene. This close-up view is being used to show us what the convict is thinking and also to show the anger. This close-up view is also used to prevent us seeing what Pip is doing when the camera zooms up on the convict. Therefore we worry for Pip and this adds to the suspense of the moment. The convict is an intimidating large man who has a lot of power over Pip. In the beginning he is always shot in darkness, whereas Pip is always shot in bright light to emphasise his innocence. This is particularly noticeable when the convict is in control, trying to tilt Pip over the gravestone. There is a cut between Pip and the convict to show Pip’s vulnerability and a close-up of his face highlights his terror. Pip is shown as the opposite to the convict and looks innocent, charming and neatly dressed. The convict however looks angry and dirty and we presume that this is what he is like and therefore regard him as a bad person. Language is also used to emphasise the convict’s aggressiveness. The convict specifically emphasises the words ‘roasted’ and also ‘tear him open’. These words are emphasised to scare Pip and also to shock the audience. It draws the audience into the story and makes us feel Pip’s intimidation. The convict’s terrifying image adds to the forbidding setting.  Julian Jarrold’s version of the convict is shown to be incredibly daunting and intimidating. Although no dialogue is spoken we can see from his fixed stare on Pip and his angry scowl that he intends to do harm to him. The convict is dressed in old dirty clothes and looks very ill groomed, this adds to the audience’s understanding of him as an escaped convict. Lean uses some effective techniques to show the characters. He shows the vast landscape with tall-silhouetted gibbets to indicate just how small and vulnerable Pip is. The use of light and dark is very effective when me meet the convict. Pip remains in the light but the convict’s face is shrouded in darkness to convince the audience of his an evil nature. Pip’s lightened appearance shows his innocence and makes the audience wonder why such a nice boy is in such a dark and gloomy place. After the confrontation, Pip is seen scrabbling home across the marshes as quickly as possible, against the same eerie landscape. The setting in Jarrold’s 1999 interpretation is less stereotypical. It is not dark and the sky is sunny. There is a very high-pitched note, which appears haunting and creepy to the audience. Just before we see Pip’s head peep out of the wheat field, from the convict’s point-of-view, we hear breathing and this causes suspense, as we cannot see anyone. The setting of a wheat field is less traditional and does not prepare us for when the convict chases Pip, as no one would expect to find a convict in the middle of a wheat field. The golden reeds add to the peaceful tranquillity of the first shot, and therefore relax the viewer. Jarrold uses his own ideas and makes the opening more intriguing and exciting. At the beginning we have no idea what is going to happen and because of this Pip’s running come as a shock, and therefore has more impact. This provides the audience with an immediate incentive to continue watching. We then follow the dramatic chase that Jarrold has constructed through a wheat field and the graveyard. Jarrold’s use of point-of-view shots give the audience a chance to feel more involved in the film and to help them to feel the confusion of the chase. The wheat field itself is Jarrold’s own notion and is not mentioned anywhere in the written novel. However, this really helps to show Pip is trying to hide but that he cannot escape.

Sunday, November 10, 2019

Liquid Chromatography Lab

Liquid Chromatography – Laboratory #18 Introduction: We are using liquid chromatography to separate the colored substances in grape-flavored drinks. We separate the component dyes, and then we separate the flavorings and citric acids. Background: Chromatography is a process that is used to separate a substance into its component parts. The separation occurs between the stationary and moving phase of the lab. The moving phase consists of a fluid and the stationary phase consists of a solid. The mixture we are trying to split up is integrated into the mobile phase.When the mobile phase interacts with the solid phase, the components of the mixture are attracted to the solid phase in varying degrees. Components with higher levels of attraction for the mobile phase result in a faster speed of transport throughout the solid phase. Components with higher levels of attraction for the solid phase result in a slower speed of transport throughout the solid phase. These differing levels o f attraction end up in separation of the mixture into component bands, which exit the system as distinct liquids. [pic] Liquid chromatography labs are composed of six main parts: . A separation column filled with a fine-grain solid. b. A solvent (mobile phase) that moves through the separation column. c. An injection system to transport the solvent to the separation column. d. A pump to force the solvent through the separation column. e. A detector to determine when the components exit the separation column. f. A recorder [pic] Although in most chromatography labs the solid phase is polar and the mobile phase is nonpolar, we are using Reverse Phase Liquid Chromatography, where the mobile phase is polar and the solid phase is nonpolar. Also read: Fluorenol PolarityWhen the mobile phase interacts with the solid phase, the polar parts of the mobile phase are attracted to each other, so they wash through the column quickly. The less polar components of the mobile phase are attracted to the nonpolar solid in the column, so they wash through the column slowly. This results in a separation of the components, whose degree is measured as the resolution. [pic] Pre-lab Questions 1. What is the process of chromatography used for? 2. In the chromatography, components of a mixture distribute themselves between the stationary phase and the mobile phase.Explain how the components can be separate with these two phases. 3. In the liquid chromatography column used in this experiment, the solid has a C18 hydrocarbon bonded to it. Would a C18 hydrocarbon be polar or nonpolar? Explain. 4. Below are the typical data for this experiment. 1 mL of a Kool-Aid solution was loaded on a Sep-Pak C18 Column. The red and blue dyes were eluted fro m the column with a constant flow of 18% isopropyl alcohol. The eluted solution was collected in a 10 mL graduated cylinder. The volumes of eluant were recoreded at the beginning and end of each color band. pic] Information: The first step in calculating the selectivity and resolution of the system is determining the volumes of eluant corresponding to the band widths and band centers for each eluted dye. a. Bandwidth W is the volume in mL of eluant containing each dye as it emerges from the column. Calculate the bandwidth W for each dye for each of the three runs and then determine the average bandwidth W average for each dye. b. Center of band, called Average Retention Volume V Rave corresponds to the center of each band.The average retention volume is calculated by taking the average starting volume for each band and adding one half the corresponding average band width. V Rave = V start + (? ) W ave Calculate the average retention volume volume V Rave for the red and blue dyes. c. For each dye, a capacity factor k' can be calculated. This term is a relative measure of the attraction of the dye for the stationary phase as compared to its attraction for the mobile phase. The equation fo capacity factor is : k' = (V Rave – V M)/V M here V Rave is the average retention volume for each dye and V M is mobile phase or eluant volume in the cartridge. V M can be estimated to be one half the cartridge volume, with the stationary phase occupying the other half. For the Sep-Pak cartridges, this V M value is . 49 mL. Calculate k' for each dye. d. A selectivity or separation factor, alpha, can now be calculated. This is the ratio of the k' values for each dye, with the larger value in the numerator. For good separation, a mobile phase is usually chosen that gives an alpha value between 2 and 10. Calculate alpha for this separation: alpha = (k' Blue)/(k' Red) e.The resolution R, a measure of how well the two dyes are separated by the column and eluant, is determined by the equation R = 2(V Rave Blue – V Rave Red)/(W Blue + W Red) where the numerator is the volume between the band centers and the denominatory represents the average band width. The greater the selectivity, the larger the numerator and therefore the greater the resolution. The resolution can also increase as the efficiency of the column increases, since this results in a lower average band width. Calculate R for this separation. Materials: Isopropyl Alcohol, 70% 50 mLIsopropyl Alcohol, 28%, 10 mL Isopropyl Alcohol, 18% 50 mL Isopropyl Alcohol, 5% 10 mL Graduated Cylinder, 10mL Graduated Cylinder, 25 mL Distilled Water, 300 mL Grape Koolaid Solution, 20 mL Sep-Pak C18 Cartridge 10 mL Syringe w/ male Luer tip Beaker, 100 mL, 3 Beaker, 50 mL, Safety Precautions: Isopropyl alcohol is inflammable and a fire hazard. Do not conduct this laboratory in the presence of flames. This alcohol is slightly toxic by ingestion and inhalation. Chemical-resistant goggles, gloves, and aprons are required. Wash and rinse hands thoroughly with soap and water after conducting the lab.Procedure Part 1: Isocratic Separation (Constant rate of flow and solvent concentration) Pretreatment of the Sep-Pak C18 Cartridge 1. Cut off the exit tube/shorter end of the cartridge at the point where it meets the body of the cartridge. 2. Load the syringe with 10mL of 70% isopropyl alcohol. 3. Connect the tip of the syringe to the long end of the Sep-Pak cartridge. 4. Pump the isopropyl alcohol through the syringe cartridge at a rate of 5-10 mL/minute. 5. Collect the alcohol in a 10 mL graduated cylinder to monitor flow rate. 6. Repeat previous steps with distilled water. Sample Injection . Use 10 mL syringe to slowly inject 1 mL of Kool-Aid solution onto the column. 2. Discard the effluent that washes out. 3. Remove the cartridge from the syringe. 4. Rinse the syringe with 10 mL of distilled water 3 times to erase Kool-Aid residue. Sample Elution 1. Fill the syringe with 18% isopropyl alc ohol eluant and attach the syringe to the Sep-Pak Cartridge. 2. Pump the alcohol through the cartridge with a flow rate of 5-10 mL/min. 3. Collect effluent in 10 mL graduated cylinder. 4. Record volume of effluent collected as first and last of colored drops of each of the dyes exit.If separation is imperfect, record data for beginning/end of intermediate purple bands. Center of the purple band acts as the end of the first band and beginning of the last. Column Regeneration Repeat measurements two more times. Between injections, wash the column with 10 mL of distilled water at the same flow rate of 5-10 mL/min. If colored residue remains, repeat preatreatment. Part 2: Step Gradient Separation Now, we change composition of the eluting liquid. We first use a polar solvent, and then we reduce the polarity of the solid phase by adding isopropyl alcohol.Through this, we wash out citric acid and flavoring oils in addition. Pretreatment of the Sep-Pak C18 Cartridge Follow the pretreatment in Part 1. Sample Injection and Component Elution 1. Inject 1 mL of Kool-Aid solution into the column. 2. Elute polar components of the mixture (citric acid and sugar) by passing 5 mL of distilled water through the column. 3. Collect effluent in the first small beaker. 4. Elute the red dye by passing 10 mL of 5% isopropyl alcohol through the column. 5. Collect effluent in the second small beaker. 6. Use 10 mL of the 28% isopropyl alcohol to elute blue dye. 7. Collect effluent in the third small beaker. . Use 10 mL of 70% isopropyl alcohol to elute nonpolar flavor oils and additives. 9. Collect effluent in the fourth small beaker. 10. Record the color of each effluent. Evaporate the solvents and examine the components. 1. Allow the solutions to evaporate and leave them overnight in the fume hood until next lab period. Label solutions properly. 2. Observe and describe contents of each of the beakers. Measure using color, odor, and appearance. Data Table Part 1: Isocratic Separation | |Red Dye |Blue Dye | | Run #1 |Run #2 |Run #3 |Run #1 |Run #2 |Run #3 | |Start of Band (mL) | | | | | | | |End of Band (mL) | | | | | | | |W (mL) | | | | | | | |Vrave (mL) | | | | | | | |K’ | | | | | | | Part 2: Step Gradient Separation Beaker |Eluant |Observations | |1 |H2O | | | | | | |2 |5% isopropyl alcohol | | | | | | |3 |28% isopropyl alcohol | | | | | | |4 |70% isopropyl alcohol | | | | | | Calculations Determine the following values and show calculations. Refer to question six in the Pre-Lab Questions. Enter results in the Part 1 data table. 1. Bandwidth W for each dye. 2. Average Retention Volume V Rave for each dye. 3. Capacity Factor k' for each dye. 4. Selectivity alpha for the two dyes with this isocratic separation. 5. Resolution R for the two dyes with this isocratic separation.Post-Lab Questions 1. What is meant by polarity of molecules? What causes differences in polarity? 2. In discussing solubility, the rule â€Å"like dissolves like† is frequently used. What does this mean? 3. Draw the structural formula of isopropyl alcohol. Explain how it differs in polarity from water. 4. For good separation of the dyes, the resolution should be greater than one. What was the value you calculated? Did the two dyes overlap as they emerged from the column, or was the separation a good one? 5. In the step gradient separation, four separate fractions were collected. How were these related to the polarities of the column and of the eluting solvent?

Thursday, November 7, 2019

The Ladders’ Signature Program Are guaranteed job offers a scam

The Ladders’ Signature Program Are guaranteed job offers a scam The end of June 2011 brought a lot of hype in the blogging world about TheLadders’ new â€Å"Signature† Program. Have you heard of it? Signature promises that â€Å"selected participants who actively engage in all components of the Signature program are guaranteed a job offer or their money back.† The price tag?   $2,495. The claim of success? 90%. [I’m taking the existence of this program, and the price tag, on faith since TheLadders’ website is seemingly impenetrable without a username and password – see www.theladders.com] Criticism of the Signature program abounds. Forbes’ Susan Adams points out what might be the obvious in her article, The Ladders Guarantees a Job Offer or Your Money Back: TheLadders self-selects the people who may enroll in the program. They don’t guarantee a job to just anyone! And, as it turns out, 75% of the people accepted into the program are already employed and looking to move up the ladder or make a lateral move into a larger company. These folks are much better positioned to succeed in their job search than the unemployed. The 90% success rate doesn’t sound quite so impressive anymore, does it? Furthermore, explains Ms. Adams, if you read the fine print you find out that participants are required to â€Å"apply to 6 well-fitted positions per month.† Hmmm†¦Ã‚   who determines what constitutes a â€Å"well-fitted† position?   What if there are not 6 positions the candidate wants to apply to? It seems the $2,495 fee will then be forfeited. For additional criticism of this aspect of the program, see   A Six Figure Job Guaranteed or your Money Back in the bnet.com blog (authored by Kimberly Weisul). And what if a participant applies to 6 jobs in order to comply with the program, even though they are not jobs she wants to accept because of location, company culture or some other factor? What if she gets an offer from one of them? She has then paid $2,495 to get a worthless job offer. The Signature program reminds me of a â€Å"deal† offered by Match.com in my internet dating days. Match, as I remember, offered 6 additional free months if I did not meet someone I liked within 6 months. The catch? I had to contact 6 people each month for 6 months to remain eligible for the offer. Eek. There just weren’t that many guys who appealed to me enough to make the effort. I contacted an average of 2 guys a month for 6 months, didn’t make a love connection, and cancelled my service. And cancelling services is what a lot of people might start doing around The Ladders. Snarky career blogger Nick Corcodilos refers to The Ladders as a â€Å"beleaguered organization† in his article, TheLadders: A lipstick pig’s death rattle? He suggests that if TheLadders CEO’s Marc Cenedella’s claims are correct, and he has 4.5 million subscribers at $35/month, then those 4.5 million are not getting the results promised by their subscription. Why else would TheLadders need to dangle a pricey â€Å"guaranteed† job offer carrot in front of these subscribers? Another suspicious promise of Signature is their claim that the program will reduce the amount of time necessary to spend on a job search from 30 to 4 hours per week. Silly me! Here I was thinking that job searching was a full-time job. It takes time to make connections and work networks, and a Manpower study recently found that 41% of successful jobhunters got their jobs through networking. Does TheLadders claim that significant networking is now unnecessary in the job search process?! I am wary of any program that encourages job searchers to stop engaging in this essential and necessarily time-consuming aspect of their search. What do you think of this grand offer by TheLadders? Would you front the dough if you were chosen as a qualified candidate? Or would you prefer to get a great resume and cover letters and find your job the old fashioned way?

Tuesday, November 5, 2019

Definition and Examples of Letters as Symbols

Definition and Examples of Letters as Symbols A letter is an alphabetic symbol such as A or a. There are 26 letters in the modern English alphabet. Among the world’s languages, the number of letters ranges from 12 in the Hawaiian alphabet to 231 principal characters in the Ethiopian syllabary. Etymology From the Latin, shape or symbol used in writing The Efficiency of the Alphabet Because letters work at the phonemic level and are unencumbered by any extra baggage of sound, they achieve maximum efficiency. Our six letters of pencil can easily be broken out and rearranged within countless other wordslien, Nile, stipend, clip,that sound nothing like pencil. Letters are the original snap-on tools: They build on each other as necessary, so you actually need fewer items in your toolkit. With 26, we capture reasonably well the approximately 500,000 words of English.(David Sacks, Letter Perfect: The Marvelous Story of Our Alphabet From A to Z. Broadway, 2004) The History of Letters From A to BThe symbol A indicated in Semitic a glottal consonant that did not exist in Greek. Its Semitic name was aleph, the initial apostrophe here indicating the consonant in question; and, because the name means ox, it has been thought to represent an oxs head, though interpreting many of the Semitic signs as pictorial characters presents as yet insuperable difficulties (Gelb 1963, pp. 140-41).   By ignoring the initial Semitic consonant of the letters name, the Greeks adopted this symbol as a vowel, which they called alpha. Beta  was ultimately somewhat modified in form to B by the Greeks, who wrote it and other reversible letters facing in either direction; in the early days of writing they wrote from right to left, as the Semitic peoples usually did and as the Hebrew is still written. From the Greek modifications of the Semitic names of the first two letters, the word alphabet is ultimately derived.(Thomas Pyles and John Algeo, The Origins and Development of the English La nguage, 3rd ed., 1982) The Roman Alphabet in Old English and Middle English [A]  linguistic connection between the Anglo-Saxons  who settled in the British Isles and other Germanic tribes is their use of the runic alphabet, developed on the continent for scratching short messages onto wood or stone. But runic writing had only a limited use in Britain; the conversion to Christianity brought with it the Roman alphabet, which was established as the principal medium for Old English written  records. Because it was devised for writing Latin rather  than English, the Roman alphabet was not a perfect fit for the Old English sound system. Latin had no th sound and consequently no letter to represent it; to fill this gap the Anglo Saxons imported  the letter thorn, à ¾, from the runic alphabet. This letter remained in use for writing English until the fifteenth century, when it developed a y-shaped appearance; it now survives in this modified form in faux archaic ye olde tea shoppe signs, where ye should properly be pronounced the.​(Simon Horobin,  How English Became English. Oxford University Press, 2016) The Lighter Side of Letters Im good friends with 25 letters of the alphabet. I dont know Y.(Comedian Chris Turner, quoted by Mark Brown in Edinburgh Fringes 10 Funniest Jokes Revealed. The Guardian, August 20, 2012)

Sunday, November 3, 2019

Nurses role Research Paper Example | Topics and Well Written Essays - 1000 words

Nurses role - Research Paper Example Nurses role Abstract The study of this research is aimed at exploring the role of nurses in prevention of the healthcare associated infections. The concept of healthcare associated infections has been defined in this research. The characteristics of healthcare associated infections have been studied. The essential conditions that lead to the transmission of healthcare associated infections to susceptible patients are identified in the research process. The various features of healthcare associated infections that distinguish it from other diseases have been studied in the research process.The nurses have been identified as the frontline people for prevention of health care associated infections. The duties and responsibilities of the nurses and the role played by them in preventing healthcare associated infections have been analyzed in this research. The various clinical methods and the medical practices adopted by the nurses have been analyzed in the research process that is useful in prevention of healthcare associated infections. Introduction The health care associated infections are the diseases that develop among the patients during the time of hospitalization. The contamination of the hospital environment and the transmission of the infectious agents affect the patients who are vulnerable to such infection. The nurses are frontline healthcare staff who can directly identify the symptoms of healthcare associated infections and could effectively treat the patients for recovery. Healthcare Associated Infections The Centre for Disease Control and Prevention, headquartered in Atlanta, USA has provided a formal definition of Healthcare Associated Infections. The health care associated infections are the diseases that affect the patients during the period of hospitalization. These patients are not affected by these diseases before hospitalization. Neither do these infections develop post hospitalization. The period of hospitalization is also counted as the time period from 48 hours to the next 10 days post hospitalization. There are three essential criteria, the fulfillment of which may lead to the transmission of healthcare associated infections. There must be a source of infected microorganism, an agent or a means of transmission of the infectious disease and a host or patient who is vulnerable to be affected by the infection. The various sources of infected microorganisms are the bacteria, viruses, fungi and protozoa. The sources of infection may also be the residual bacteria on the skin, intestine, respiratory system, etc of the patients. These infections are difficult to suppress and as a result of this the hospital environment, equipments, floors and exposed surfaces may get contaminated (Bullock,  Clark and  Rycroft-Malone, 2012). These act as agents for transmission. The infection is transmitted to the susceptible host or the patient who gets infected due to deficiency in the immunity of the host patient. The lack of immunity m ay be due to suffering from anemia, leukemia, diabetes, etc. The susceptibility of the host may also develop due to prolonged hospitalization on account of severe illness. Role of Nurses: Prevention of healthcare associated infections The role of nurses is extremely vital in prevention of healthcare associated infections. The nurses are the first point of resistance who are responsible to take necessary actions for prevention of the healthcare associated infections. The daily precautionary practices adopted by the nurse help in preventing the transmission of the health associated infection to the susceptible patients. The nurses have a direct control over recognizing the source of infection, monitoring the environmental conditions

Friday, November 1, 2019

20 Things 20-Year-Olds Don't Get Assignment Example | Topics and Well Written Essays - 250 words

20 Things 20-Year-Olds Don't Get - Assignment Example The assignment "20 Things 20-Year-Olds Don't Get" analyzes the article which is a good piece fit for young graduates or those yet to complete their studies. It gives pieces of advice to young people on how to face life once they come out of school. It targets both the employed young people and those yet to secure jobs who share the objective of excelling in life. The tips are applicable in the real life and are vital in overcoming the challenges that come with employment, especially for the young generation. Young people require reminder on the necessity to protect and maintain a good reputation. Damaged reputation follows you wherever you go. On working hard, the author is not very right. Being first to arrive at work and the last to leave does not translate to being effective in the workplace. It is better to work smart and achieve the set goals than spending more hours at the workplace. Hard work does not depend on the number of hours spent working but on the quality and timely delivery of targets. The point that I will take from the article is advancing in technical skills to complement my degree. According to the article, this will boost the chances of getting employment. The author also stresses on networking as a strategy for ensuring employment. It is true that securing jobs today rely more on the people that one knows than skills possessed by the person. Expanding on the network guarantees the timely receipt of information about employment opportunities.